Statistical investigations is actually in keeping with a beneficial multiplicative dating involving the in the-risk alleles and smoking (Desk 2)
We looked at to possess affairs of each SNP for the journal off pack-numerous years of smoking to choose when they differed regarding the multiplicative relationships inherent about logistic regression designs
Such as for instance, good nonsmoker having step one risk allele getting SNP rs10958409 into the chromosome 8 might have an otherwise of 1.forty-eight in order to have an IA, an effective 20-seasons tobacco user without duplicates associated with the chance allele will have an or of five.04, and a 20-pack-season tobacco user which have step one during the-chance allele would have an or out-of seven.46 (see footnote in Table 2 having reason). No shot attained mathematical importance indicating a great multiplicative matchmaking offered a great fit towards the analysis (if any proof to possess supramultiplicative or lower than multiplicative relationship).
Table 2. Logistic Regression Activities for step 3 SNPs and you will Smoking (Pack-Years) towards the Chromosomes 8 and you may 9 (Activities Modified getting Decades)
